EXAMINE THIS REPORT ON CONOLIDINE ALKALOID FOR CHRONIC PAIN

Most a short while ago, it has been discovered that conolidine and the above derivatives act within the atypical chemokine receptor 3 (ACKR3. Expressed in very similar parts as classical opioid receptors, it binds to a big range of endogenous opioids. Contrary to most opioid receptors, this receptor functions being a scavenger and will not activate